The pathophysiology of residual sleepiness in treated obstructive sleep apnoea (OSA) remains poorly understood. Animal models ...

Introduction It is well established that when associated with infection, pleural effusions carry a significant morbidity and mortality. Sonographic septations are assumed to be associated with poor ...

Background Sampling of peripheral pulmonary lesions (PPLs) abutting the pleura carries a higher risk of pneumothorax and complications. Although typically performed with image-guided transthoracic ...

Background Whether inhaled corticosteroids (ICSs) reduce major adverse cardiovascular events (MACEs) in people with chronic obstructive pulmonary disease (COPD) is debated. Objectives To establish, ...

Correspondence to British Thoracic Society, 17, Doughty Street, London WC1N 2PL, UK; bts{at}brit-thoracic.org.uk and Dr Charlotte E Bolton, Nottingham Respiratory Research Unit, University of ...

Background The natural history and time course of the onset of exacerbation events of chronic obstructive pulmonary disease (COPD) is incompletely understood. Methods A prospective cohort of 212 ...

Background The Global Obstructive Lung Disease (GOLD) 2011 revision recommends the multidimensional assessment of COPD including comorbidities and has developed a ...

Air Travel Working Party: Dr R K Coker (chair), Dr D A R Boldy, Dr R Buchdahl, Mr D Cramer, Professor D Denison, Wing Commander D P Gradwell, Professor J M B Hughes, Dr J A Innes, Dr A O C Johnson, Dr ...

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...

Background Despite biomarker-guided initiation, non- or loss of response to biologic therapy occurs in a minority of patients with severe asthma. In cases of treatment failure, it is important to ...

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To determine whether asthma alone can cause irreversible airflow obstruction 42 men and 47 women with chronic asthma (mean duration 22 (SD 13) years) without evidence of other disease likely to cause ...